{"id":137853,"date":"2019-11-25T17:25:33","date_gmt":"2019-11-25T14:25:33","guid":{"rendered":"https:\/\/www.dailymail.co.uk\/news\/article-7721235\/Scientists-hope-periods-suspended-animation-help-cure-cancer.html?ns_mchannel=rss&amp;ito=1490&amp;ns_campaign=1490"},"modified":"2019-11-25T17:25:33","modified_gmt":"2019-11-25T14:25:33","slug":"scientists-hope-periods-of-suspended-animation-could-help-cure-cancer","status":"publish","type":"post","link":"http:\/\/wardoon.net\/so\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer\/","title":{"rendered":"Scientists hope periods of suspended animation could help cure cancer"},"content":{"rendered":"<p class=\"mol-para-with-font\">When they\u2019re looking for ideas for their next futuristic blockbuster, Hollywood\u2019s movie moguls could do worse than visit the University of Maryland Medical Centre in the American city of Baltimore.<\/p>\n<p class=\"mol-para-with-font\">In 2012, doctors there carried out one of the world\u2019s first successful face transplants. And earlier this year they pioneered using drones to transport a donor kidney.<\/p>\n<p class=\"mol-para-with-font\">Both were remarkable achievements but they pale compared with news that surgeons at the hospital have placed a human being into a state of what is being called \u2018suspended animation\u2019.<\/p>\n<p class=\"mol-para-with-font\">No details are known of the patient, who is thought to have arrived with a stopped heart, having lost at least half their blood. These symptoms are consistent with a gunshot or stab wound \u2014 common in a city with a notoriously high violent <a href=\"https:\/\/www.dailymail.co.uk\/news\/crime\/index.html\" id=\"mol-fd8b46e0-0f13-11ea-9405-5ff22a67511e\">crime<\/a> rate.<\/p>\n<div class=\"artSplitter mol-img-group\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img loading=\"lazy\" decoding=\"async\" id=\"i-6ef5ee08f8c55902\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-1.jpg\" height=\"423\" width=\"634\" alt=\"Biologists are also studying larger animals able to achieve a state of suspended animation. Maria Berg von Linde, a cardiologist at Sweden\u2019s Orebro University, said:&nbsp;\u2018The bear has solved most of the health challenges faced by humans. Understanding and applying [how] could lead to major discoveries with implications for treating human disease'&nbsp;(stock image)\" class=\"blkBorder img-share\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"i-6ef5ee08f8c55902\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-1.jpg\" height=\"423\" width=\"634\" alt=\"Biologists are also studying larger animals able to achieve a state of suspended animation. Maria Berg von Linde, a cardiologist at Sweden\u2019s Orebro University, said:&nbsp;\u2018The bear has solved most of the health challenges faced by humans. Understanding and applying [how] could lead to major discoveries with implications for treating human disease'&nbsp;(stock image)\" class=\"blkBorder img-share\"><\/p>\n<\/div>\n<p class=\"imageCaption\">Biologists are also studying larger animals able to achieve a state of suspended animation. Maria Berg von Linde, a cardiologist at Sweden\u2019s Orebro University, said:&nbsp;\u2018The bear has solved most of the health challenges faced by humans. Understanding and applying [how] could lead to major discoveries with implications for treating human disease&#8217;&nbsp;(stock image)<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Surgeons operating on such trauma cases have barely any time to save a victim\u2019s life. At a normal human body temperature of 37c (99f), we can survive only about five minutes without a heartbeat to pump oxygen to our cells. After that, the damage to the brain is irreversible and survival rates are around five per cent.<\/p>\n<p class=\"mol-para-with-font\">In this case, however, the patient\u2019s body was chilled to around 10\u201315c (50\u201359f) by replacing their blood with an ice-cold saline solution. This almost completely stopped both their brain activity and the chemical reactions taking place in their body\u2019s cells, giving the surgical team up to two hours to fix their injuries.<\/p>\n<div class=\"artSplitter mol-img-group\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img loading=\"lazy\" decoding=\"async\" id=\"i-dd6ba11857978534\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-2.jpg\" height=\"378\" width=\"634\" alt=\"Studies of mice have identified a protective mechanism that kicks in when their body temperature is lowered, preventing the loss of brain cells, and the connections between them, seen in Alzheimer\u2019s disease and dementia&nbsp;(stock image)\" class=\"blkBorder img-share\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"i-dd6ba11857978534\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-2.jpg\" height=\"378\" width=\"634\" alt=\"Studies of mice have identified a protective mechanism that kicks in when their body temperature is lowered, preventing the loss of brain cells, and the connections between them, seen in Alzheimer\u2019s disease and dementia&nbsp;(stock image)\" class=\"blkBorder img-share\"><\/p>\n<\/div>\n<p class=\"imageCaption\">Studies of mice have identified a protective mechanism that kicks in when their body temperature is lowered, preventing the loss of brain cells, and the connections between them, seen in Alzheimer\u2019s disease and dementia&nbsp;(stock image)<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Whether the person concerned survived once they had been warmed up, had their blood restored and their heart restarted has not been disclosed. But Professor Samuel Tisherman and his team plan to carry out the procedure on more patients in a trial, with the results out in late 2020.<\/p>\n<p class=\"mol-para-with-font\">Revealing his research in an exclusive interview with New Scientist magazine, Professor Tisherman admitted that seeing someone in the limbo between life and death was \u2018a little surreal\u2019.<\/p>\n<p class=\"mol-para-with-font\">Yet such techniques may one day be commonplace, with medicine already cooling the human body to extremely low levels, bringing metabolism to a near-stop.<\/p>\n<p class=\"mol-para-with-font\">This has been inspired by amazing stories of survival, where both children and adults have been clinically dead for hours \u2014 but survived because their bodies had become incredibly cold.<\/p>\n<p class=\"mol-para-with-font\">Take radiologist Dr Anna Bagenholm who, in 1999, was skiing in Norway when she crashed through the frozen surface of a stream and became trapped under the ice. After 40 minutes she suffered a cardiac arrest. Her friends finally managed to drag her free, but a rescue helicopter took 90 minutes to arrive.<\/p>\n<p class=\"mol-para-with-font\">When she arrived at hospital, her heart had stopped for more than two hours but the extreme cold had protected her vital organs from damage, putting her in a state of suspended animation, despite the oxygen deprivation.<\/p>\n<p class=\"mol-para-with-font\">Four-and-a-half hours after Dr Bagenholm fell through the ice, her body had slowly been warmed and her heart restarted. She made an almost full recovery and eventually she returned to work.<\/p>\n<div class=\"artSplitter mol-img-group\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img loading=\"lazy\" decoding=\"async\" id=\"i-4d20f0a37ba78904\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-3.jpg\" height=\"431\" width=\"634\" alt=\"From hibernating brown and black bears, for example, we might learn how to prevent and treat a wide range of diseases (stock image)\" class=\"blkBorder img-share\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"i-4d20f0a37ba78904\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-3.jpg\" height=\"431\" width=\"634\" alt=\"From hibernating brown and black bears, for example, we might learn how to prevent and treat a wide range of diseases (stock image)\" class=\"blkBorder img-share\"><\/p>\n<\/div>\n<p class=\"imageCaption\">From hibernating brown and black bears, for example, we might learn how to prevent and treat a wide range of diseases (stock image)<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Her story led to doctors worldwide developing a technique called \u2018therapeutic hypothermia\u2019. Victims of heart attack, injury and stroke, and newborn babies who have suffered a lack of oxygen at birth, are cooled to extremes, to slow the process of deterioration dramatically and give medical teams time to treat them.<\/p>\n<p class=\"mol-para-with-font\">The difference between such cases and the latest development in the U.S. is that these patients are brought to a temperature of about 35c (95f) which, although it constitutes hypothermia, is still far higher than the 10-15c achieved in Baltimore.<\/p>\n<p class=\"mol-para-with-font\">That was inspired by an incident early in Professor Tisherman\u2019s career, dealing with a youth who had been stabbed in the heart.<\/p>\n<p class=\"mol-para-with-font\">\u2018He was a healthy young man just minutes before, then suddenly he was dead. We could have saved him if we\u2019d had enough time,\u2019 he says.<\/p>\n<p class=\"mol-para-with-font\">Beyond giving surgeons such as Professor Tisherman more time to operate, such extremely low temperatures could one day help combat cancer, with research suggesting that patients in this state might be able to tolerate far higher doses of radiation without healthy tissues being harmed.<\/p>\n<p class=\"mol-para-with-font\">Italian physicist Professor Marco Durante, one of the world\u2019s leading radiotherapy experts, has hailed this state of \u2018synthetic torpor\u2019 as the \u2018future\u2019 of cancer treatment from which even the terminally ill can benefit.<\/p>\n<p class=\"mol-para-with-font\">\u2018You wake up the patients and they are cured. That is our ambition,\u2019 he said.<\/p>\n<p class=\"mol-para-with-font\">Of course, inducing hypothermia can be dangerous, potentially damaging vital cells and disrupting natural healing. Yet we may be better equipped to deal with such challenges than we assume.<\/p>\n<p class=\"mol-para-with-font\">Studies of dwarf lemurs, which live only in Madagascar and are man\u2019s closest genetic relatives known to hibernate, show that during periods of dormancy, which last up to eight months, their normal heart rate of 180 beats a minute can drop to as low as four. Body temperature, which usually hovers at about 36c (97f), can plunge to an almost-freezing 5c.<\/p>\n<div class=\"artSplitter mol-img-group\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img loading=\"lazy\" decoding=\"async\" id=\"i-5b26d63649722905\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-4.jpg\" height=\"423\" width=\"634\" alt=\"Revealing his research in an exclusive interview with New Scientist magazine, Professor Tisherman admitted that seeing someone in the limbo between life and death was \u2018a little surreal\u2019 (stock image)\" class=\"blkBorder img-share\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"i-5b26d63649722905\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-4.jpg\" height=\"423\" width=\"634\" alt=\"Revealing his research in an exclusive interview with New Scientist magazine, Professor Tisherman admitted that seeing someone in the limbo between life and death was \u2018a little surreal\u2019 (stock image)\" class=\"blkBorder img-share\"><\/p>\n<\/div>\n<p class=\"imageCaption\">Revealing his research in an exclusive interview with New Scientist magazine, Professor Tisherman admitted that seeing someone in the limbo between life and death was \u2018a little surreal\u2019 (stock image)<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">\u2018To all intents and purposes, they are dead,\u2019 says Sheena Faherty, a biologist at Duke University in North Carolina.<\/p>\n<p class=\"mol-para-with-font\">And since these animals share about 97 per cent of our genetic make-up, she suggests \u2018humans might already have the mechanisms that confer the ability to hibernate present in our genome\u2019.<\/p>\n<p class=\"mol-para-with-font\">Biologists are also studying larger animals able to achieve a state of suspended animation.<\/p>\n<p class=\"mol-para-with-font\">From hibernating brown and black bears, for example, we might learn how to prevent and treat a wide range of diseases, according to Maria Berg von Linde, a cardiologist at Sweden\u2019s Orebro University.<\/p>\n<p class=\"mol-para-with-font\">\u2018If humans spent half the year in a physically inactive state without eating, defecating or urinating, they would suffer heart failure, thrombosis, organ injuries, blood poisoning and more.<\/p>\n<p class=\"mol-para-with-font\">\u2018The bear has solved most of the health challenges faced by humans. Understanding and applying [how] could lead to major discoveries with implications for treating human disease.\u2019<\/p>\n<div class=\"artSplitter mol-img-group\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"><img loading=\"lazy\" decoding=\"async\" id=\"i-c1ebdcef93224426\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-5.jpg\" height=\"636\" width=\"634\" alt=\"Understanding the secrets of hibernation may also open the gateway for humankind\u2019s dream of colonising faraway planets such as Mars (stock image)\" class=\"blkBorder img-share\"><\/div>\n<p><img loading=\"lazy\" decoding=\"async\" id=\"i-c1ebdcef93224426\" src=\"http:\/\/wardoon.net\/wp-content\/uploads\/2019\/11\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer-5.jpg\" height=\"636\" width=\"634\" alt=\"Understanding the secrets of hibernation may also open the gateway for humankind\u2019s dream of colonising faraway planets such as Mars (stock image)\" class=\"blkBorder img-share\"><\/p>\n<\/div>\n<p class=\"imageCaption\">Understanding the secrets of hibernation may also open the gateway for humankind\u2019s dream of colonising faraway planets such as Mars (stock image)<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Neuroscientists at Cambridge and Leicester universities have discovered that hibernating animals have a still more astonishing trick which may potentially provide a cure for two modern plagues of ageing.<\/p>\n<p class=\"mol-para-with-font\">Studies of mice have identified a protective mechanism that kicks in when their body temperature is lowered, preventing the loss of brain cells, and the connections between them, seen in Alzheimer\u2019s disease and dementia.<\/p>\n<p class=\"mol-para-with-font\">\u2018We can now work towards finding a means to develop drugs that might mimic the protective effects of cold on the brain,\u2019 says lead researcher Professor Giovanna Mallucci.<\/p>\n<p class=\"mol-para-with-font\">Understanding the secrets of hibernation may also open the gateway for humankind\u2019s dream of colonising faraway planets such as Mars, frustrated not least by the psychological effects of such a long space odyssey on the crew.<\/p>\n<p class=\"mol-para-with-font\">In one Russian study, a seven-person team were locked inside a mock capsule for 110 days. Only one month in, a ten-minute fist-fight between two Russian crew members left blood spattered on the walls.<\/p>\n<p class=\"mol-para-with-font\">Then the crew\u2019s Canadian medic was twice sexually assaulted by the team commander.<\/p>\n<p class=\"mol-para-with-font\">To address such problems, Nasa scientists have long been investigating putting the crew into a state of hibernation.<\/p>\n<p class=\"mol-para-with-font\">Far-fetched perhaps. But, until last week, so too was the idea of putting a human into suspended animation \u2014 a reminder that what seems outlandish one day can become reality the next.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When they\u2019re looking for ideas for their next futuristic blockbuster, Hollywood\u2019s movie moguls could do worse than visit the University of Maryland Medical Centre in the American city of Baltimore. In 2012, doctors there carried out one of the world\u2019s first successful face transplants. And earlier this year they pioneered using drones to transport a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":137854,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"facebook_10221280388112155_325455220908133":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[23],"tags":[],"class_list":["post-137853","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-english-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Scientists hope periods of suspended animation could help cure cancer - Wardoon<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wardoon.net\/so\/scientists-hope-periods-of-suspended-animation-could-help-cure-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists hope periods of suspended animation could help cure cancer - Wardoon\" \/>\n<meta property=\"og:description\" content=\"When they\u2019re looking for ideas for their next futuristic blockbuster, Hollywood\u2019s movie moguls could do worse than visit the University of Maryland Medical Centre in the American city of Baltimore. 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In 2012, doctors there carried out one of the world\u2019s first successful face transplants. 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